Izingxube ze-Berberine ne-Silymarin Zisiza Impilo Yenhliziyo Ye-Metabolic
Muva nje, i-meta-ukuhlaziywa kwezivivinyo ezinhlanu ezingahleliwe, eziphindwe kabili-zezimpumputhe, ze-placebo{2}}ezilawulwayo ezilawulwayo (RCTs) ezenziwe abacwaningi abavela eNyuvesi yase-Bologna, iNyuvesi yase-L'Aquila kanye neNyuvesi yasePalermo e-Italy ithole ukuthi imikhiqizo eyenziwe equkethe i-berberine ne-silymarin ingathuthukisa izinga likashukela egazini kanye nokuzila ukudla. Umbiko wabonisa ukuthi amazinga kashukela egazi kwabafundayo ehle kakhulu, ngokwesilinganiso sehle ngo-7.5 mg/dl. Imiphumela yocwaningo ishicilelwe kuJournal Plant Therapy Research.
Umphumela we-berberine ekwehliseni i-lipid waziwa kahle. Ukuhlaziywa kwemeta-kwezifundo zomtholampilo ezingu-27, ezibandakanya ababambiqhaza abangu-2569, kwaqinisekiswa ngokucacile abacwaningi. Uma kuqhathaniswa nokuhlaziywa kwe-meta-, imiphumela yabonisa ukuthi i-silymarin eyengeziwe (i-berberine) ingaba nomthelela omuhle ku-lipid kanye nemetabolism kashukela kubantu, okuvumela ukusetshenziswa kwemithamo ephansi ye-berberine, ngaleyo ndlela kwehlise ingcuphe yokungakhululeki emathunjini ehambisana kakhulu nomthamo.
Eqinisweni, uma kucatshangelwa ukubekezelelwa kwethamo eliphansi (i-berberine) kungase futhi kube nokubaluleka komtholampilo okubalulekile, ngoba i-hypercholesterolemia iwukuhambisana nomtholampilo okungenazimpawu, ukunamathela emithini yokwehlisa i-lipid-kadokotela iphansi uma kuqhathaniswa, futhi izinga lokuyeka liphezulu nakakhulu lapho kwenzeka izenzakalo ezimbi noma ukusabela kwezidakamizwa.
Ososayensi base-Italy babuyekeze izincwadi ngokuhlelekile futhi bathola ama-RCT amahlanu afanelekile afakwe -ekuhlaziyweni kwabo. Imininingwane iqhamuke kubantu abangama-497. Ubude besikhathi socwaningo babusukela ezinyangeni ezi-3 kuye kweziyi-12, ne-berberine kumithamo engama-500 noma i-1000 mg/ngosuku kanye ne-silymarin ngemithamo engu-105 noma engu-210 mg/ngosuku.
Imiphumela yabonisa ukuthi ukwelashwa okuhlangene kunganciphisa i-cholesterol ephelele ngo-25 mg/dl, i-triglyceride ngo-28 mg/dl, i-cholesterol ye-LDL ngo-29 mg/dl kanye ne-cholesterol ye-HDL ngo-6 mg/dl. Ucwaningo olukhona lubonise ukuthi i-berberine ne-silymarin ingathuthukisa i-lipid yegazi namazinga kashukela egazini, futhi le nhlanganisela yemisoco ingase isetshenziselwe ukukhuthaza impilo ye-metabolic yenhliziyo.
U-Wellgreen ungumhlinzeki ochwepheshe we-herbal extarct. Uma ungathanda ukwazi imininingwane eyengeziwe, wamukelekile ukuthi usithinte.
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