I-Houttuynia uhlobo lomuthi wendabuko waseShayina osetshenziswa kakhulu ekudleni nasemthini. Ibizwa ngokuthi i-houttuynia ngenxa yokuthi isiqu namaqabunga ayo anephunga elimnandi ngemva kokuhlikihlwa nokuchotshozwa. Inemisebenzi yokususa ukushisa kanye nokukhipha ubuthi, ukuqeda ama-carbides nokukhipha ubomvu, okokukhipha isisu nokuconsa. I-H. cordata yamalungiselelo emithi asetshenziswa ngokuvamile ane-compound herba houttuyniae, houttuynia eyedrops, heartleaf houttuynia herb injection, the new cordate houttuynia element injection ye-sodium, njll., inokushisa okucacile, i-detoxification, i-lishi, isetshenziswa kabanzi ekwelapheni izifo zokuphefumula, ukutheleleka kwe-urinary tract, izifo zesikhumba, eyaziwa ngokuthi imithi yamaShayina kanye ne-gynec. ama-antibiotic{{6}ebanzi.
a. Isithako esisebenzayo se-Houttuynia cordata
Kuze kube manje, ama-compounds angu-220 ahlukaniswe futhi ahlonzwa ku-Houttuynia cordata, kuhlanganise nama-flavonoids, amafutha ashisayo, ama-phenolic acid, ama-alkaloids, ama-terpenoids, i-phenylethanol glycosides nama-phenylpropanoids. Izingxenye eziyinhloko ezisebenzayo ziyi-flavonoids namafutha aguquguqukayo.
Okuqukethwe kwama-flavonoid ku-Houttuynia cordata kuphezulu, ikakhulukazi i-quercetin, i-luteolin, i- kaempferol, njll., ehlanganiswe noshukela ukuze kwakhiwe ama-glycosides, ingenye yezingxenye eziyinhloko ezisebenzayo ze-houttuynia cordata. E-Houttuynia cordata, amaqabunga ayenokuqukethwe okuphezulu kakhulu kwe-flavonoid ephelele, elandelwa yiziqu nezimpande, futhi okuqukethwe kwengqikithi ye-flavonoid eziqwini namaqabunga kwakuhluke kakhulu.
INaphtha njengomthombo oyinhloko we-h. I-cordata ithumela iphunga elimnandi lezinhlanzi, kanye nezingxenye zayo eziyinhloko ezisebenzayo. I-Heartleaf houttuynia herb injection, i-houttuynia eyedrops, nokunye ukulungiswa kwemithi yomdabu yaseShayina ukukhipha uwoyela oguquguqukayo osetshenziswa njengomuthi, okuhlanganisa i-decyl acyl acetaldehyde (isici se-cordate houttuynia) iwumphumela oyinhloko wokwelapha wezinto ezilwa{2}}nokuvuvukala kwe-antimicrobial, kodwa i-corynia, inqubo ye-cordate eyenzeka kalula ukusabela kwe-distillation njenge-oxidation kanye ne-polymerization kanye ne-condensation.
I-Houttuynia nayo iqukethe i-palmitic acid, i-oleic acid, i-stearic acid, i-aristolocholic acid namanye ama-organic acid, kanye ne-glucose, i-fructose, i-galactose, i-rhamnose nabanye ushukela, ama-amino acid kanye nezakhi zokulandelela nazo zicebile kakhulu.
b. Umsebenzi we-Pharmacological we-Houttuynia cordata
I-Antioxidant:Isamba se-flavonoid nama-polyphenols e-Houttuynia cordata abe nekhono elibalulekile lokulahla i-hydroxyl radical ne-superoxide anion radical, futhi abonisa ubudlelwano obuhle bomphumela wedosi. Umphumela we-antioxidant we-flavonoid isiyonke wawunamandla kunalowo kavithamini C nama-polyphenols. Ngaphezu kwalokho, i-polysaccharides evela ku-Houttuynia cordata ingakhuphula imisebenzi ye-superoxide dismutase ne-glutathione peroxidase ku-serum nesibindi samagundane, ithuthukise umthamo we-antioxidant womzimba, futhi inciphise okuqukethwe kwe-malondialdehyde ezicutshini zesibindi.
Ivimbela{{0}ukuvuvukala ne-bacteriostatic:Amafutha abalulekile e-Houttuynia cordata anganciphisa ukuvezwa kwe-COX-2 mRNA kanye nephrotheni kuma-macrophages e-peritoneal yegundane enziwa i-lipopolysaccharide, futhi avimbele ukukhishwa kwe-PGE2 ukuze kuzuzwe-umsebenzi ovimbela ukuvuvukala. I-Flavonoids ehlukanisiwe ne-ethanol ekhishwe ku-Houttuynia cordata ivimbele kakhulu ukukhiqizwa kwama-biomarker avuthayo i-IL-6 kanye no-NO kumaseli wamaphaphu epithelial kanye nama-alveolar macrophages. Amafutha abalulekile e-Houttuynia cordata anomphumela onamandla wokulwa namagciwane kubhaktheriya e-gram-negative (E. coli, i-Denatella vulgaris, i-pseudomonas aeruginosa), ne-houttuynia cordata iyisakhi esisebenzayo sokulwa namagciwane. I-Houttuynia inomphumela othile we-antibacterial ku-Escherichia coli, i-Staphylococcus aureus, i-Pseudomonas aeruginosa, i-Candida albicans ne-candida yeast.
I-Antiviral:I-Houttuynia cordata inomphumela ovimbelayo ezinhlobonhlobo zamagciwane, futhi indlela yayo ethile yizinto ezisebenzayo zokuloba ezidingekayo ukuze kuvinjwe ukuphindaphinda kwegciwane. I-Houttuynia extract ibe nomthelela osobala wokuvimbela igciwane lase-Asia, igciwane lomkhuhlane kanye negciwane le-hemorrhagic fever. Amafutha abalulekile e-Houttuynia cordata abe nomthelela othile ovimbela umkhuhlane A, umkhuhlane B kanye nama-mumps virus.
I-anti{0}}isimila:I-Houttuynia cordata kanye ne-neohouttuynia cordata nazo zibe nokuvinjwa okubalulekile kwe-mouse ascites carcinoma, futhi izinga eliphakeme kakhulu lokuvinjelwa ku-mitosis yamaseli omdlavuza lalingu-45.7%. Umphumela ovimbelayo we-neohouttuynitin ungase uhlobane nokwanda kwezinga le-cAMP kumaseli omdlavuza. I-Houttuynia alcohol extract idala ukufa kweseli okuhleliwe kwe-human melanoma A375 ngokwenza kusebenze i-cystaprotease{4}}indlela encikile kanye ne-phosphorylation ye-P38 ehlotshaniswa nokwehliswa kwe-HMGB1. Ingqikithi yokukhishwa kwe-flavonoid ye-Houttuynia cordata inganqanda ukukhula kwamaseli e-SiHa tumor futhi yenze i-apoptosis, inikeze isisekelo sesayensi se-houttuynia cordata elwa-nomdlavuza womlomo wesibeletho.
Thuthukisa ukuzivikela:Ukukhishwa kwe-Houttuyniae kungashukumisa ukwanda kwama-lymphocyte egundane, kukhuphule ingxenye yamaseli e-CD4+ kanye ne-CD8+, futhi kukhulise ukukhiqizwa kwe-IL-2 kanye ne-IL-10 ngama-lymphocyte we-spleen yegundane, konke okungathuthukisa ukuzivikela komzimba. Umjovo we-methyl n-nonone, ingxenye eyinhloko kawoyela obalulekile we-Houttuynia cordata, uthuthukise kakhulu izinga le-serum hemolysin, ukuqina kokulibaziseka kwe-hypersensitivity, i-phagocytosis yama-macrophages kanye nomsebenzi wamaseli ababulali bemvelo, ngendlela encike kumthamo.
c. Ukusetshenziswa komtholampilo kwamafomu emithamo ahlukene
I-Houttuynia piece
Ithebhulethi njengohlobo lwemithamo oluvame kakhulu lomuthi welungelo lobunikazi waseShayina, ukusebenziseka kwayo akufanele kubukezwe kancane. Kubikwa ukuthi umphumela wamaphilisi e-compound houttuynia kuma-mumps muhle. Ngaphezu kwalokho, ukwelashwa komkhuhlane obandayo, i-bronchitis kunomphumela omuhle.
I-Houttuynia eye drops
I-Houttuynia eye drops inomphumela omuhle, ukuphepha okuphezulu kanye nenani lezomnotho elisobala ekwelapheni ubhubhane lwe-keratoconjunctivitis kanye ne-acute catarrh conjunctivitis. Inethuba elibanzi lohlelo lokusebenza lomtholampilo ekwelashweni komtholampilo kwe-acute catarrh conjunctivitis yohlobo lokushisa komoya. 120 izehlakalo (amehlo angu-235) ze-acute bacterial conjunctivitis zilashwe nge-houttuynia eyedrops. Isilinganiso esisebenzayo se-acute bacterial conjunctivitis sasingu-93.10%, kanti leso sifo esiwubhubhane conjunctivitis sasingu-89.92%.
Umjovo we-Houttuynia
Izifo zokuphefumula:Umjovo we-Houttuynia unemiphumela ethile yomtholampilo ku-pneumonia, i-bronchitis engapheli, ukutheleleka komgudu wokuphefumula kanye ne-pharyngitis, isifo sofuba nezinye izifo. Umjovo we-Houttuynia uhlanganiswe ne-cephalosporin ekwelapheni i-bronchitis engapheli kubantu asebekhulile, imiphumela yabonisa ukuthi izinga eliphumelelayo lalingu-83.4%, 12.6% liphakeme kune-cephalosporin eqenjini lokulawula.
Izifo zesistimu yokugaya:Umjovo we-Houttuynia unganciphisa ngokuphawulekayo amazinga e-PCT, HS-CRP, IL-2 nezinye izinkomba zokuvuvukala ezinganeni ezine-viral enteritis, ukuze kudambise ukuvuvukala. Isamba sesilinganiso esisebenzayo sasingu-97.6%, ngaphezulu kuka-79.9% eqenjini lokwelapha elijwayelekile.
Izifo ze-Urologic: Iziguli ze-96 ezinokutheleleka kwe-urinary tract zikhethwe njengento yocwaningo. Ngemuva kwenyanga eyodwa yokwelashwa ngomjovo we-Ciprofloxacin hydrochloride kanye nomjovo we-Houttuynia hydrochloride, izinga lokwelapha lomjovo we-houttuynia hydrochloride lalingu-56.3%, laliphezulu kakhulu kunelo lomjovo we-Ciprofloxacin hydrochloride elingu-31.3%.
Izifo zabesifazane:Iziguli ezingama-3260 zelashwa ngokuphathwa kwasendaweni kwe-intrauterine kwe-Houttuynia injection polyethylene catheter, okuhlanganisa namacala ayi-1330 e-adjuncitis engapheli, izehlakalo ezingama-980 ze-endometritis engapheli, izehlakalo ezingama-950 zokuvuvukala kwe-pelvic okungapheli, kanye namacala angama-540 eqembu lokulawula. Imiphumela Isamba sezinga elisebenzayo lesifo esingelapheki sokuvuvuka kwe-pelvic lalingama-84%. Inani eliphelele elisebenzayo lalingama-83% ku-endometritis engapheli kanye nama-80% ezifweni ezingapheli zokuvuvukala kwe-pelvic.
