Njengengcweti "yokulwa{0}}nomdala" oqeqeshiwe, awukwazi kanjani ukushintsha ngokushesha ubuchwepheshe bokwandisa impilo ezandleni zakho?
I-Artemisia annua, eyaziwa nangokuthi i-artemisia scoparia, iwuhlobo lwekhambi olungasetshenziswa njengemifino yasendle kanye nomuthi, kanti kwezinye izindawo, luphakelwa ngisho nezingulube. Kodwa ucwaningo olusha lwesayensi luye lwathola ukuthi lesi sitshalo esimangalisayo singandisa impilo.
Thina abacwaningi bathola ukuthi ukukhishwa kwe-artemisia kwandisa isikhathi sokuphila sika-c. ama-elegans ngamaphesenti angama-41 ngaphandle kokuphazamisa amandla ayo okuzala ngokukhuthaza ukugcinwa kwamafutha kanye nokululama komzimba. Okutholakele kushicilelwe Feb{3}} ku-The Journals of Gerontology: Series A, ijenali yamazwe ngamazwe ye-Gerontology.
Ucwaningo luthole ukuthi i-nematodes ephakela okukhishiwe ikhulise ukubonakaliswa kwe-δ 9 fatty acid desaturase, iphrotheni ethuthukisa ukuguqulwa kwama-saturated fatty acids angenampilo abe ama-monounsaturated fatty acid. Nakuba amafutha asengamafutha afanayo kodwa ashintsha indlela yokuwagcina, lawa “mafutha” awagcini nje ngokuyithinti impilo kodwa futhi anomthelela ekuphileni isikhathi eside.
Idatha yokuhlola ibonise ukuthi ama-nematode anikezwe i-artemisia extract njengabantu abadala anesandiso esibalulekile sesikhathi sokuphila esingu-37-41%. Ngisho nama-nematode aqala ukuwathatha eseminyakeni ephakathi ayephila cishe ngamaphesenti angu-20 isikhathi eside. Ngaphezu kwalokho, nakuba ukungenelela okuningi okulwa nokuguga kuthinta ikhono lesilwane lokuzala, ukukhishwa kwe-artemisia akuzange kuthinte kabi ikhono le-nematode lokuzala. AmaNematode akhiqiza inani elifanayo lenzalo njengeqembu lokulawula futhi aqhubeka nokuzala isikhathi eside.
Abacwaningi bathole ukuthi okukhishiwe kusebenza ngokushukumisa ukudluliselwa kwe-nuclear ye-transcription factor Daf-16 /FOXO, elawula i-fat metabolism. Ku-daf-16 nematodes eguquliwe, i-artemisia annua extract ayizange ibe nomthelela owandisa ukuphila nhlobo.
Kubalulekile ukuqaphela ukuthi nakuba ukukhishwa kwe-Artemisia scoparia kungokwandisa indlela yamafutha angagcwalisiwe ukuze kunwetshwe ukuphila kwesikelemu uma ukuphakelwa kwe-artemisia scoparia okukhishwe ngesikhathi esifanayo, kuqhubeka nokwengeza ekudleni kwesikelemu ama-monounsaturated fatty acids, angenawo nje umphumela ophindwe kabili kodwa into enhle kakhulu, angase abeke engcupheni impilo ye-nemato ende.
