Ucwaningo lwakamuva olushicilelwe kulo Mfumfu ku-International Journal of Molecular Sciences lunikeza imininingwane emisha ngekhono le-curcumin lokubambezela ukuguga. Kuyaziwa ukuthi ama-mesenchymal stem cell (MSCs) atholakala kakhulu emnkantsheni, nokuthi iningi lezicubu ze-homeostasis zomzimba zincike emgogodleni, ngakho-ke ukuguga kwezinto eziphilayo kanye nokuthuthukiswa kwezifo ezingapheli ezihlobene nokuguga kubangelwa kakhulu ukuguga kwama-MSC. Kulolu cwaningo, i-curcumin ibuyisele i-autophagy evinjelwe kumnkantsha we-MSC ngenkathi ithuthukisa ukuzwela komnkantsha we-MSC.
Ucwaningo oluseduze olushicilelwe i-Hunan University of Traditional Chinese Medicine ngokufanayo lubonise izinzuzo zalo zokuguga-ezilibazisayo, ngaphandle kokuthi kulokhu, i-curcumin yahlanganiswa ne-aspirin kumodeli ye-Cryptobacterium hidradenum. Idatha ibonise ukuthi inhlanganisela yalokhu kokubili yenze kusebenze i-antioxidant gene expression ku-Cryptobacterium hidradenum futhi kubambezeleke ukuguga ezilwaneni eziyimodeli.
Ngamanye amazwi, i-curcumin inamandla ekuvimbeleni nasekubambezeleni ukuguga, futhi nakuba ubufakazi bomtholampilo bungatholakali, i-curcumin iye yasetshenziswa kabanzi ukuze kudambise izifo ezihlukahlukene zabantu, futhi izici zayo zokulwa{0}} nokuguga zimane nje ziwuqweqwe lwekhekhe. Eqinisweni, namuhla ucwaningo lokulwa-lokuguga seluya ngokuya luvuthwa, i-spermidine, i-metformin nezinye izinto kade zaqiniswa endaweni yokusakaza ephezulu{3}}yendilinga yokuguga, amandla e-turmeric e-anti{4}}okuguga empeleni anjani, kusalindwe ubufakazi bocwaningo obulandelayo.
